Digestive Disorders, Genetics and Epigenetics

Crohns_Ulcerative

 

Digestive Disorders….

Crohn’s disease has an energetic, or vibrational, underlying cause conditioned by mental and emotional patterns of thoughts and feeling-reactions that maintain an underlying condition of stress in the physical body. These underlying stress-producing energetic patterns keep the body in a fight or flight response mode.

Any treatment to bring about a “cure” of Crohn’s disease must necessarily include addressing this underlying energetic cause. Without this factor properly addressed and cleared, all treatments, medical and/or alternative, will only bring about relief and management of the condition.
Crohn’s disease is usually preceded by chronic indigestion. The cause of Crohn’s disease, diverticulitis, colitis and irritable bowel syndrome (IBS) is probably chronic indigestion.

Here is the definition of Crohn’s disease taken from the Mayo Clinic
“Crohn’s disease is a chronic inflammatory disease of the intestines. It primarily causes ulcerations (breaks in the lining) of the small intestines, but can affect the digestive system anywhere from the mouth to the anus. It is named after the physician who described the disease in 1932. It also is called granulomatous enteritis or colitis, regional enteritis, ileitis, or terminal ileitis.”

(Note: The Ileum is another name for the last section of the small intestines, the part that connects to the large intestines (or ascending colon), which is where the appendix is also located.)

To answer the question “What causes Crohn’s disease?” one must first answer the question “What causes inflammation in the intestines?” Right? So, let’s think this through by following the digestive process. But first let’s look at the inflammatory process.

The Cause of Inflammation
What causes inflammation is the immune system. It’s the body’s way of dealing with infection. Infection is the immune system’s way of dealing with foreign matter that is not being eliminated. Food is foreign matter to the body. It is supposed to be digested and then eliminated from the intestinal tract.  There are also genetic polymorphisms like TNF, IL6 and CRP that contribute to excessive inflammation. (While still controversial, studies of depression and IBD are currently being linked to TNF levels.)

Remember, the inside of the alimentary canal, from the mouth to the rectum, is outside the body, although it runs through it. In other words, it is part of the body’s immediate environment, just as dirt on your skin is external to the body. In fact, the lining of the intestines is made from the same matrix of tissue (ectoderm) as skin. It’s a membrane. In other words, it’s skin.

The brain and nervous system are also made from the same matrix, the ectoderm. Skin is an organ of elimination and has intelligence. It is a very permeable membrane, however, letting in what will nourish the body and eliminating what is toxic and not handled by the other organs and glands of elimination. The pH of the skin is a crucial aspect of its integrity. High acidity will break it down. Inflammation is created by the immune system, which is very pervasive throughout the intestines and colon, in order to deal with the foreign substance that is irritating the membrane.

It is literally a fire, a localized febrile condition created to burn up toxins and dying cells.

Food that is not properly digested will cause acidity in the intestines. Undigested protein will rot causing putrefaction. Undigested carbohydrates will ferment. Undigested fats will go rancid. Rancid fats destroy tissue immediately upon contact. This is why it is not good to eat rancid seeds and nuts or use rancid cooking and salad oils. They also destroy HDL, the so called “good” cholesterol. Cholesterol is essential to the structural composition of the cell wall . . . every one of the 100 trillion cells that make up your body.

Digestion of Proteins and Carbohydrates
Protein is broken down and digested in the stomach by hydrochloric acid (HCL). Hydrochloric acid is secreted by the parietal cells lining the stomach at a pH (potential of Hydrogen) of 0.8, very acidic, and by the time it mixes with the stomach contents its pH increases to about 2.5. Pepsin is the activating enzyme for HCL.e food during mastication – which is why it is important to chew food thoroughly before swallowing. Lypase is the activating enzyme for the digestion of fats.  Environmental factors like food transportation have reduced the enzymes in food that help us to digest that food.  Food is frequently picked before it is ripe.

HCL production in the stomach begins to decline around age 45, and our enzyme reserve runs low, so it is supportive of digestion to take digestive enzymes and probiotics.

Poor Digestion and Stress
The function of the parietal cells, like all cells in the body, depends largely upon adrenalin. Stress puts the body in fight or flight mode sending most of the adrenalin to the muscle cells.

The body is not interested in growth and healing when it is focused on survival or running away from a stressor, such as a charging bull, a stressful job or lifestyle, or long-term grieving and mental and emotional distress. Toxins inhaled or ingested bring on stress just as surely as any other external stressors. This is why cigarette smoking keeps the lining of the stomach inflamed, mainly from the chemicals (some 300 of them in the paper and tobacco).  Endocrine disruptors in the environment, like plug in chemical air fresheners contribute to stress. The genetic polymorphism MTHFR tends to contribute to a buildup of toxins. IBS, Crohns and Ulcerative Colitis are conditions associated with this genetic polymorphism.  MTHFR can also impact the creation of betaine in the methylation cycle.  Many people also have genetic mutations impacting their ability to digest carbohydrates  like ACE, PPARG, ADRB2, FABP2 and TCF7L2.

Fat genetic mutations will also be challenging for the digestive tract like FTO, LPL, FABP2, APOC3 and APOA2.

Poor nutrition puts the body cells in a state of starvation stress as well. When there’s stress, the parietal cells of the stomach shut down the production of hydrochloric acid, rendering protein digestion problematic. Mental and emotional stress also produces acidosis throughout the body.

When protein is not digested properly produces putrid matter. Putrefaction produces organic acids, which will erode the stomach and intestinal linings. The acids of putrefaction and fermentation are what cause “acid indigestion” and “heart burn.”

It is not the hydrochloric acid that causes these symptoms, including ulcers. In fact, it is the lack of hydrochloric acid that creates the condition of indigestion that leads to putrefaction of proteins. So when a person has “heart burn” after eating, while antacids do relieve the symptoms, they also cancel out the hydrochloric acid needed for digestion.

So when a person has “acid indigestion” and “heartburn” s/he needs some digestive support.

To take chemicals that stop the production of digestive stomach acids only adds insult to injury. We have to add digestive acids to the stomach not eliminate them. Pharmaceutical grade Aloe Juice for calming the digestive tract, antioxidants for healing it, Active B Complex (5-MTHF) to support MTHFR, digestive enzymes and probiotics are one of the solutions. IV or Isotonic delivery is important because the digestive tract is stressed. Isotonic delivery skips the whole process and goes right to the cells that need relief.  Isotonic Wellmune is also recommended as it contains patented beta-glucans that activate your innate immunity to better react to and neutralize foreign invaders of your body. It can also benefit the “depression”  associated with the genetic polymorphism TNF.

The Digestive Process and the pH Factor
The gallbladder and pancreas produce copious amounts of sodium-rich bile and alkaline juices respectively to emulsify fat and buffer the 2.5 pH acids of digestion in the chyme (stomach contents) coming out of the stomach into the duodenum, the first 12 inches of the small intestines. The intestines, which are ideally happy with a 5.8 to 6.2 pH, would be distressed and burned by 2.5 pH content.
So, it is important that the gallbladder and pancreas produce their alkaline substances to buffer this acid. Otherwise duodenal ulcers may develop. The colon, on the other hand, likes a more acidic environment – for one thing, to keep yeast and fungus from growing and thereby giving rise to infection.

What can cause these alkaline substances to be depleted of alkalizing sodium? Well, for one thing, over consumption of acid-producing foods – grains and proteins – which use a lot of acid-buffering sodium. What builds up sodium reserves? Vegetables, especially celery and cucumbers, and some fruits, such as prunes, plums and blueberries, are alkaline producing foods that build up your sodium reserves. These alkaline-producing foods should ideally make up 80% of our diet.

When bile loses it alkalinity, it becomes thick and therefore cannot easily flow through the small common-bile duct. Fat is not emulsified and therefore hardens to form stones. Calcium will precipitate out of solution and crystallize, creating calcium stones. When bile does not flow into the duodenum through the common-bile duct, the acid of the chyme does not get properly buffered and the fats are not emulsified. This creates an acid condition that will burn the small intestines, causing irritable bowel (IBS) and colitis.

Bacteria, viruses and other pathogens will thrive in this acid environment. This leads to inflammation and infection, the immune system’s way of dealing with pathogens. Crohn’s disease develops as the lining of the intestines begins to get raw, eaten up by these organic acids. This is why it will appear as “raw hamburger meat” in a colonoscopy. In this compromised condition, bacteria and viruses, along with undigested proteins and other toxins, easily enter the blood stream through the “leaky gut,” causing so-called “food allergies,” as well as infection throughout the body, including the kidneys and bladder, organs of elimination of toxic waste fluids.

Symptom Relief without side effects

Pharmaceutical grade Aloe Juice has anti-bacterial, anti-viral and anti-carcinogenic properties.  It calms and soothes skin, especially burning skin inside and out. Most Aloe product are not pharmaceutical grade so it is best to get the recommendation of a certified health professional. Antioxidants will repair cellular damage and scavenge free radicals. Isotonic delivery is recommended for optimal bioavailability.

5-MTHF (activated folate) will help the methylation cycle and DNA repair and functioning.  Digestive Enzymes and Probiotics will help digestion and boost and support good bacteria in the gut. Many health professionals have written books on how bad industrialized food is now.  We are seeing epidemics of digestive disorders in young people. This generation faces the worst toxic burden so far. GMOs have BT toxin injected into their DNA. Much more glyphosate is used on GMO food with surfactants (Roundup) that make it worse.  It is patented as an antibiotic therefore likely contributes to stronger toxic bacteria that are resistant.  The World Health Organization has classified glyphosate as a class 1 carcinogen. Organic food is recommended.  Eliminate endocrine disruptors from the environment as much as possible.

THE CURE

The “cure” of Crohn’s disease lies in the healing of the lining of the intestinal wall, factoring in genetics and epigenetics. It also includes treating and clearing the underlying energetic patterns of stress, as mentioned at the start of this article.

Emotional Factors

In her wonderful and popular book, “You Can Heal Your Life,” Louise Hay suggests that behind inflammation in the colon (ileitis), which is whiat Crohns is, may be a deep sense of fear and worry of not being “good enough.” This deeply rooted pattern was likely put there early in childhood by a well-meaning parent who tried to motivate a child by telling her how stupid she is, screaming and berating her for not being able to do anything right.

A new thought pattern she offers could be: “I love and approve of myself. I am doing the best I can. I am wonderful. I am at peace.”

Genetics

This infographic identifies all of the genetic variants named in this article. It is a snapshot of the 45 genetic polymorphisms that each have 3 independent clinical studies showing a change in expression with a change in lifestyle. The company does not sell DNA to pharmaceutical companies. These are my results.  Notice I have a very high sensitivity to carbohydrates and medium sensitivity to fats.  I knew that from my experience but I did not know I had genetics that put me at risk for Celiac Disease.  The B vitamin snapshot shows I have MTHFR. I have used all the protocols I describe.  Other symptoms of mine that have disappeared are allergies, sinus headaches, night terrors, IBS and heart palpitations.  Notice I also have a need for extra Omega III and Vitamin D as well as cruciferous and alium vegetables.  (Curcumin in the form of BCM-95 with tumeric and added broccoli concentrate can also benefit in a pinch if you can’t get your 6-12 servings of vegetables in.  That is tough for anyone working full time. To have quality food you darn near have to grow your own.  Add  in lack of nutrients in the soil, premature harvesting, pesticides, methyl mercury fallout from burning coal, pharmaceutical contamination of water, compromised environmental policies by moneyed corporate interests controlling politics, etc. can we really expect to achieve optimal health just from eating food?)

DNAFIT

This article took me 12 years to write.  It is compiled from many cutting edge professionals, one of the top genetic scientists in the world, Dr. Keith Grimaldi, my work with cutting edge Allopathic health professionals and CAMs, and my own urgency to help someone I love deeply.  There is plenty of science to back all of it up.  I learned by Googling, Pubmed, science based sites, scientists and health professionals who have success. We all need science but none of us should have to wait the years it will take for clinical studies and medical schools to catch up, especially when the protocols are benign and effective and there are pharmaceutical and insurance moneyed interests blocking many progressive moves toward prevention and optimal health.  To learn more in detail about protocols go to my youtube channel, Kathy Kaufman Videos.  Write me at kathy@criticalhealth.org.

A special thanks to my friend Michael Sweringen of Microleadership.  He helped lead me to all of the climate and environmental information that got me thinking about epigenetics.  And Dr. Keith Grimaldi, a brilliant genetic scientist and good man.

And lastly, the FDA has not evaluated any of this information. If only they would.


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